Acute Hepatitis: Symptoms, Causes, Treatment & Prevention

Sudden inflammation of the liver tissue or injury to hepatocytes (liver cells), leading to impaired liver function, are the hallmarks of many different conditions collectively referred to as acute hepatitis.

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Treatment Overview

Sudden inflammation of the liver tissue or injury to hepatocytes (liver cells), leading to impaired liver function, are the hallmarks of many different conditions collectively referred to as acute hepatitis. The duration of inflammation and damage to the liver tissue determines whether a case of hepatitis is considered acute or chronic.

Acute hepatitis is the term used to describe a period of inflammation or injury of liver cells that lasts for less than six months. Conversely, chronic hepatitis is the term used to describe liver cell injury or inflammation that lasts longer than six months. Acute hepatitis calls for immediate treatment and abstaining from the cause.

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What is Acute Hepatitis?

An inflammation of the liver is referred to as hepatitis. There are various factors that can lead to liver inflammation, such as viruses (viral hepatitis), chemicals, drugs, alcohol, certain genetic disorders, or an overactive immune system that unintentionally targets the liver (autoimmune hepatitis). Acute hepatitis is liver inflammation flares up and goes away quickly. It is characterized by elevated liver indices in liver function tests for less than six months.

Acute Hepatitis
Types of Acute Hepatitis

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Types of Acute Hepatitis

Hepatitis A, B, C, D, and E are the five viruses that cause the various types of viral hepatitis. Unwashed food and contaminated water are the main ways that hepatitis A is transmitted. It is the most contagious, particularly in young children, but it also has the lowest chance of harming the liver. It is typically mild and goes away entirely in six months.

Hepatitis B can be passed from mother to child as well as through contact with contaminated blood, syringes, needles, or bodily fluids. It's a chronic illness that, after many years of viral infection, can sometimes result in permanent liver damage, liver cancer, and cirrhosis of the liver. The contaminated blood can spread hepatitis C, or it can be passed from mother to child during childbirth. In the long run, it can also result in cirrhosis and liver cancer. Only those with a hepatitis B infection can have hepatitis D.

Most cases of hepatitis E occur in South America, Asia, and Africa. When taken excessively or in very high doses, some normally safe medications can be toxic to the liver and result in hepatitis, also known as drug-induced hepatitis. These include vitamin A and acetaminophen (Tylenol).

Autoimmune hepatitis is a type of liver inflammation that happens when the overactive immune system attacks the body cells, mainly in the liver.

Causes of Acute Hepatitis

An acute viral hepatitis infection is the most frequent infectious cause of acute hepatitis.

However, a broad range of noninfectious causes can also cause acute hepatitis. These include, but are not limited to:

  • Drug intoxication causing drug-induced hepatitis
  • Alcohol consumption causing alcoholic hepatitis
  • Immunologic responses causing autoimmune hepatitis & primary biliary cholangitis
  • Indirect insults resulting from biliary tract dysfunction causing cholestatic hepatitis
  • Pregnancy-related liver diseases
  • Shock
  • Liver cancer
Causes of Acute Hepatitis

Symptoms of Acute Hepatitis

Following are the main symptoms of acute hepatitis:

Complications of Acute Hepatitis

Certain complications of acute hepatitis are:

Diagnosis of Acute Hepatitis

  • Medical History: Consult a liver specialist doctor in Pune, India for assistance immediately if you're experiencing symptoms associated with hepatitis. Tell doctors about your medicines, any medical conditions you may have (including genetic abnormalities), or a history of alcohol abuse.
  • Liver function tests (LFT): LFT measures the concentrations of different proteins and enzymes in your blood. Your liver's functionality may be determined by the levels of these proteins and enzymes.
  • Other blood tests: In addition, a doctor may conduct a full blood count to screen various diseases.
  • Imaging tests: An ultrasound, CT scan, or MRI are examples of imaging technologies that can be used to visualize your liver's structural integration
  • Liver biopsy: This test is commonly performed to assess liver damage. Your doctor takes a small fragment of your liver during a liver biopsy so it can be studied in a lab.
Diagnosis of Acute Hepatitis
Treatment of Acute Hepatitis

Treatment of Acute Hepatitis

The precise cause linked to the acute hepatocyte injury determines how acute hepatitis should be treated. The most common infectious causes of acute hepatitis are hepatitis A and E. These infections typically have a self-limited clinical course and go away with supportive care, which includes IV fluids, antiemetics, and symptomatic therapy, in two to four weeks. Apart from that, patients should abstain from alcohol, other drugs that may be hepatotoxic, and over-the-counter supplements. They ought to be taught how to lower their chance of infecting other people as well.

Consideration should be given to patients who exhibit signs and symptoms of acute liver failure, as acute acetaminophen ingestion is a common noninfectious cause of acute hepatitis leading to acute liver failure. Following the acquisition of an initial history and acetaminophen testing, prompt treatment with N-acetylcysteine should be started as soon as possible.

Conclusion

The cause of the direct harm to the hepatocytes determines the likely outcome of acute hepatitis. Reducing the chances of disabilities and fatalities requires prompt identification of the cause behind the acute hepatitis and its appropriate management. Make an appointment with your healthcare provider if you have a history of heavy alcohol use and/or liver disease symptoms. They will examine your liver, evaluate any potential harm, and assist you in altering your lifestyle for the better.

Frequently Asked Questions

Q1: Is there a cure for acute hepatitis?

A: Vaccines against types C, D, and E of hepatitis are not available. Once hepatitis is acquired, there is no recovery. The goals of treatment are to relieve symptoms, stop more liver damage from occurring, and try to reverse any already existing damage. The majority of acute hepatitis cases go away with time.

Q2: What are the first seven hepatitis symptoms?

A: Fever, exhaustion, appetite loss, nausea, vomiting, abdominal pain, dark urine, light-colored stools, joint pain, and jaundice are some of the signs and symptoms of acute hepatitis. It can take decades for chronic viral hepatitis symptoms to appear.

Q3: Can acute hepatitis cause death?

A: Hepatitis A and E infections nearly always result in recovery and don't require treatment. When patients contract the B, C, or D viruses, their infection may become chronic, and some may develop cirrhosis or liver cancer. On the other hand, the infection is curable if caught early enough.

Q4: Which course of action is best for acute viral hepatitis?

A: Even the severe cases of acute HBV infection appear to benefit from the use of lamivudine, adefovir dipivoxil, and other antiviral therapies.

Q5: How long is the duration of acute hepatitis?

A: Acute hepatitis is most frequently caused by infectious hepatitis A and E, which typically have a self-limited clinical course and resolve in two to four weeks with supportive care.

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